British journal of anaesthesia
The most recent articles from:
Br J Anaesth
2014
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Retraction Of Publication
Notice of formal retraction of an article by Dr Joachim Boldt.
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Randomized Controlled Trial
Crystalloid or colloid for goal-directed fluid therapy in colorectal surgery.
Goal-directed fluid therapy has been shown to improve outcomes after colorectal surgery, but the optimal type of i.v. fluid to use is yet to be established. Theoretical advantages of using hydroxyethyl starch (HES) for goal-directed therapy include a reduction in the total volume of fluid required, resulting in less tissue oedema. Recent work has demonstrated that new generations of HES have a good safety profile, but their routine use in the perioperative setting has not been demonstrated to confer outcome benefit. ⋯ Goal-directed fluid therapy is possible with either crystalloid or HES. There is no evidence of a benefit in using HES over crystalloid, despite its use resulting in a lower 24 h fluid balance.