British journal of anaesthesia
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Editorial Comment
Restrict relaxants, be aware, and know the limitations of your depth of anaesthesia monitor.
Interesting editorial accompanying Dr Peter Schuller's excellent study of BIS values in awake, paralysed volunteers.
The editors make a very interesting point critiquing the probabilistic, database-based approach to processed-EEG awareness monitors like BIS: (emphasis added)
summary"This database-driven approach may have limitations, in particular for the detection of intraoperative wakefulness: it is very unlikely that data from an awake and paralyzed subject are included in this database. Therefore, the resulting anaesthesia index has not been trained with a dataset that contains this clinical situation..."
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Comparative Study Clinical Trial
Pulmonary blood volume measured by contrast enhanced ultrasound: a comparison with transpulmonary thermodilution.
Blood volume quantification is essential for haemodynamic evaluation guiding fluid management in anaesthesia and intensive care practice. Ultrasound contrast agent (UCA)-dilution measured by contrast enhanced ultrasound (CEUS) can provide the UCA mean transit time (MTT) between the right and left heart, enabling the assessment of the intrathoracic blood volume (ITBV(UCA)). The purpose of the present study was to investigate the agreement between UCA-dilution using CEUS and transpulmonary thermodilution (TPTD) in vitro and in vivo. ⋯ ISRCTN90330260.
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Multicenter Study Clinical Trial Observational Study
Predictors for postoperative nausea and vomiting after xenon-based anaesthesia.
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Randomized Controlled Trial
A Randomised feasibility study to assess a novel strategy to rationalise fluid in patients after cardiac surgery.
After cardiac surgery, patients receive large amounts of fluid in the Intensive Care Unit (ICU). We plan to conduct a multi-centre randomised controlled trial, of a conservative fluid regime, in patients after cardiac surgery, and have reported results of a feasibility study that evaluated efficacy and safety of the proposed regime. ⋯ Australia New Zealand Clinical Trials Registry www.anzctr.org.au (ACTRN12612000754842).