British journal of anaesthesia
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Randomized Controlled Trial
Gradual withdrawal of remifentanil infusion may prevent opioid-induced hyperalgesia.
The aim of this study was to examine if gradual withdrawal of remifentanil infusion prevented opioid-induced hyperalgesia (OIH) as opposed to abrupt withdrawal. OIH duration was also evaluated. ⋯ NCT 01702389. EudraCT number 2011-002734-39.