British journal of anaesthesia
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Multicenter Study
Patterns in medication incidents: A 10-yr experience of a cross-national anaesthesia incident reporting system.
Medication-related adverse events (MRE) in anaesthesia care are frequent and require a deeper understanding if we are to prevent medication harm. ⋯ NCT03615898.
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Syringe infusion pumps are used for the precise continuous administration of intravenous drugs. Their compliance and mechanical deficiencies have been found to cause considerable start-up delays, flow irregularities during vertical displacement, as well extensive delays of occlusion alarms at low infusion rates. The aim of this study was to evaluate the performance of several modern syringe infusion pumps at low infusion rates and the impact on drug concentration. ⋯ Problems with the performance of syringe infusion pump assemblies can have considerable impact on plasma drug concentration when highly concentrated short-acting cardiovascular drugs are administered at low flow rates. The problems, which affected all assemblies tested, are mainly related to the functional principle of syringe infusion pumps and will only partially be solved by incremental improvements of existing equipment.
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Letter Multicenter Study Observational Study
A prospective multicentre observational study on perioperative analgesia practices for total knee arthroplasty in France: the KNEEONE survey.
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Observational Study
Association between postoperative delirium and postoperative cerebral oxygen desaturation in older patients after cardiac surgery.
Near-infrared spectroscopy non-invasively measures regional cerebral oxygen saturation. Intraoperative cerebral desaturations have been associated with worse neurological outcomes. We investigated whether perioperative cerebral desaturations are associated with postoperative delirium in older patients after cardiac surgery. ⋯ NCT02532530.