British journal of anaesthesia
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Review Meta Analysis
Pharmacological interventions for the prevention of renal injury in surgical patients: a systematic literature review and meta-analysis.
The aim of this systematic review was to summarise the results of randomised controlled trials (RCTs) that have evaluated pharmacological interventions for renoprotection in people undergoing surgery. ⋯ There are multiple effective pharmacological renoprotective interventions for people undergoing surgery.
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Review Meta Analysis
Patient blood management interventions do not lead to important clinical benefits or cost-effectiveness for major surgery: a network meta-analysis.
Patient blood management (PBM) interventions aim to improve clinical outcomes by reducing bleeding and transfusion. We assessed whether existing evidence supports the routine use of combinations of these interventions during and after major surgery. ⋯ In randomised trials, PBM interventions do not have important clinical benefits beyond reducing bleeding and transfusion in people undergoing major surgery.