British journal of anaesthesia
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Pholcodine consumption greatly increases the risk of NMBD anaphylaxis (OR 14.0).
pearl -
Observational Study
Cerebral autoregulation in the operating room and intensive care unit after cardiac surgery.
Cerebral autoregulation monitoring is a proposed method to monitor perfusion during cardiac surgery. However, limited data exist from the ICU as prior studies have focused on intraoperative measurements. Our objective was to characterise cerebral autoregulation during surgery and early ICU care, and as a secondary analysis to explore associations with delirium. ⋯ Metrics of cerebral autoregulation are altered in the ICU, and may be clinically relevant with respect to delirium. Further studies are needed to investigate these findings and determine possible benefits of autoregulation-based MAP targeting in the ICU.