British journal of anaesthesia
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Review Meta Analysis
Pre-hospital tracheal intubation in severe traumatic brain injury: a systematic review and meta-analysis.
Severe traumatic brain injury (TBI) continues to be a leading cause of death, particularly in young adults. Severe TBI contributes to significant socioeconomic burden secondary to the long-term disability, impacting the individual and their family, and wider society. The aim of this study was to determine whether establishing a pre-hospital definitive airway was beneficial to mortality and morbidity when compared with no pre-hospital airway. ⋯ CRD42021234439.
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Review Meta Analysis
Patent foramen ovale and perioperative stroke in noncardiac surgery: a systematic review and meta-analysis.
Patent foramen ovale (PFO) is associated with perioperative stroke in noncardiac surgery. The magnitude of this association was assessed in a systematic review and meta-analysis. ⋯ The presence of a patent foramen ovale is associated with a large and consistent increase in odds of stroke across all explored surgical settings. Prospective trials should further explore this association by systematically assessing patent foramen ovale and stroke prevalence and identifying a specific population at risk. This is crucial for the elaboration of prevention plans and may improve perioperative outcomes.
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Review Meta Analysis
Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis.
Preemptive analgesia may improve postoperative pain management, but the optimal regimen is unclear. This study aimed to compare the effects and adverse events of preemptive analgesia on postoperative pain and opioid consumption. ⋯ PROSPERO CRD42021232593.