International journal of clinical practice
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Int. J. Clin. Pract. · Mar 2021
Atypical and unusual morphological variants of cutaneous leishmaniasis.
Cutaneous leishmaniasis (CL) is a skin disease characterised by prolonged nodulo-ulcerative lesions of the skin that heals with atrophic scar. Clinical features of CL vary depending on the type of parasite and host immune resistance. The aim of this study was to investigate the clinical features of atypical and unusual morphological variants of CL patients diagnosed in our clinic. ⋯ In conclusion, rare clinical forms of CL are presented in this study. It should be kept in mind that CL may have very different clinical features and should be considered in the differential diagnosis of eczema, psoriasis, erysipelas, sporotrichosis, paronychia and verrucous lesions.
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Int. J. Clin. Pract. · Mar 2021
Clinical TrialIntralesional low dose methylprednisolone for the treatment of active phase peyronie's disease: a single center, preliminary prospective non-randomised study.
There are a few types of drugs that can be used in the active phase of Peyronie's disease. Methylprednisolone is a corticosteroid with a strong anti-inflammatory effect. In this study, we aimed to evaluate the effect of intralesional low-dose methylprednisolone treatment on patients in the active phase of Peyronie's disease. ⋯ In order to recover the symptoms and signs, new and easily accessible drugs are required for use in the acute period of Peyronie's disease. In this context, treatment with intralesional low-dose methylprednisolone in acute phase Peyronie's Disease is a promising and safe treatment option.
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Int. J. Clin. Pract. · Mar 2021
Treatment Intensification in Type 2 Diabetes Management after the Failure of Two Oral Hypoglycemic Agents: A Non- Interventional Comparative Study.
The safety and efficacy of treatment approaches in patients with type 2 diabetes mellitus (T2DM) after the failure of two oral hypoglycemic agents (OHAs) was studied. ⋯ Insulin as add-on therapy with OHAs is an option for the management of T2DM where glycemic control is insufficient with two OHAs.
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Int. J. Clin. Pract. · Mar 2021
Observational StudyEvaluation of Online Counselling Services Based on Turkish Web-based Pharmacy Care Setting: A retrospective Observational Study.
To determine the types of online pharmacy care services provided by the clinical pharmacists regarding identification of medication-related problems, provision of counselling services for health and disease conditions alongside medications' counselling for patients seeking online consultation about health, medication and lifestyle concerns based on Turkish web-based pharmacy care setting(WPCS). ⋯ The WPCS could be considered as an additional option for the clinical pharmacist to provide care services regarding identification of medication-related problems, provision of counselling about health and disease conditions alongside different medication counselling to improve health conditions and proper pharmacotherapy management.
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Int. J. Clin. Pract. · Mar 2021
Impact of the multidisciplinary antimicrobial stewardship team intervention focusing on carbapenem de-escalation: a single-center and interrupted time series analysis.
As a result of the constant increase in carbapenem resistance amongst gram-negative bacteria in several countries, the inappropriate use of carbapenems must be reduced. Antimicrobial stewardship programmes (ASPs) aim to improve carbapenem usage by implementing interventions, including the promotion of the de-escalation (DE) strategy. Thus, this study aimed to evaluate the impact of this strategy on carbapenem use based on a clear definition of DE. ⋯ The PPRF strategy implemented by the AST could improve the carbapenem usage by increasing the DE rate of carbapenem.