International journal of clinical practice
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Int. J. Clin. Pract. · Aug 2021
Rectal Spacers in Patients with Prostate Cancer Undergoing Radiotherapy: A Survey of UK Uro-Oncologists.
To understand the awareness and use of rectal spacers for prostate cancer patients undergoing radical radiotherapy in the United Kingdom. ⋯ The current use of rectal spacers by UK uro-oncologists for patients with localised or locally advanced prostate cancer receiving radiotherapy is low and largely restricted by resourcing issues.
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Int. J. Clin. Pract. · Aug 2021
Case ReportsToxoplasma gondii Infection by Serological and Molecular Methods in Schizophrenia Patients with and without Suicide Attempts: An Age-Sex-Matched Case-Control Study.
The opinion that latent Toxoplasma gondii infection is having a broadly asymptomatic projection has now been interrogated, in specific due to the echoed association between the latent infection and an elevated incidence of schizophrenia or even suicide attempts. Notwithstanding conducted studies aimed to understand this feasible link are restricted. ⋯ This case-control study enlightens additional demonstration to the belief that T gondii infection would be an underlying component for the pathophysiology of schizophrenia. Regardless of the clarity results of this study, this supposition warrants further endorsement.
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Int. J. Clin. Pract. · Aug 2021
Observational StudyAdmission blood lactate levels of patients diagnosed with cerebrovascular disease effects on short and long-term mortality risk.
Our study was carried out on patients admitted to the emergency ward with acute stroke symptoms that were subsequently diagnosed with cerebrovascular disease. We aimed to examine the relationship between these patients' admission lactate levels and their 1-, 3-, and 12-month mortality rates in order to evaluate the prognostic value of lactate levels. ⋯ Our study found that hyperlactatemia was associated with a higher risk of 1-, 3-, and 12-month mortality, suggesting that it has predictive prognostic value. In the future, we believe that prospective observational studies and/or large-scale retrospective studies will be of great value in providing more insight into this topic.
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Int. J. Clin. Pract. · Aug 2021
The relationship between serum uric acid level and uric acid / creatinine ratio with COPD severity (stable or acute exacerbation) and the development of cor pulmonale.
There are studies reporting that uric acid elevation is a marker for hypoxemia and pulmonary hypertension secondary to some diseases. ⋯ Serum uric acid level and uric acid/creatinine ratio were found to be higher in patients with exacerbation of COPD and those developing cor pulmonale. Consequently, it suggests that serum uric acid level and serum uric acid/creatinine ratio may be a stimulating laboratory test for the severity of COPD and the development of COPD induced cor pulmonale.
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Int. J. Clin. Pract. · Aug 2021
Evaluation of kidney function tests in HIV-positive patients receiving combined antiretroviral therapy.
Human immunodeficiency virus is a chronic infection that attacks the immune system of the human body, particularly CD4 T lymphocytes. Combined antiretroviral therapies are highly effective in virological suppression of human immunodeficiency virus infection. It has been shown that some retroviral therapies have a higher nephrotoxicity potential. As a result of renal injury, serum creatinine increases and the estimated glomerular filtration rate is reduced. The aim of our study was to assess changes in kidney function during a 24-month period in HIV-positive patients who were begun on combined antiretroviral therapy. ⋯ The use of TDF-containing regimens causes renal dysfunction. Therefore, we recommend close monitoring of renal function, especially in patients treated with TDF.