International journal of clinical practice
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Int. J. Clin. Pract. · Aug 2021
Randomized Controlled TrialA Double-Blind, Controlled, Crossover Trial of Amlodipine on Iron Overload Status in Transfusion Dependent ꞵ-Thalassemia Patients.
This study examined whether administration of amlodipine could improve myocardial iron loading status in patients with transfusion dependent β-thalassemia (TDT), through a placebo-controlled, crossover study. ⋯ Amlodipine might improve myocardial MRI T2* and serum ferritin level compared to placebo. However, larger clinical studies are needed to confirm the results.
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Int. J. Clin. Pract. · Aug 2021
Multicenter StudyThe Effect of Risk Factors on Surgical and Oncological Results in High - Risk Prostate Cancer: A Multicenter Study of the Urooncology Society, Turkey.
To evaluate the effect of risk factors and selected surgical methods on operative and oncological results of patients undergoing radical prostatectomy (RP) with high-risk prostate cancer (HRPC). ⋯ RP alone is an effective treatment in the majority of patients with HRPC and PLND did not affect the progression rates after RP. According to the number of pre-operative high-risk features, as the number of risk factors increases, there is a need for additional treatment.
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Int. J. Clin. Pract. · Aug 2021
Randomized Controlled TrialAntimicrobial and hand hygiene effects of Tea Tree Essential Oil disinfectant: A randomized control trial.
Hand hygiene is paramount in preventing healthcare-associated infections in medical environments and the spread of infectious diseases in non-medical environments. ⋯ The study confirmed that tea tree oil disinfectant is effective for hand disinfection. Accordingly, tea tree oil disinfectants may be introduced to nursing practice as a new hand hygiene product to prevent and reduce healthcare-associated infections.
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Int. J. Clin. Pract. · Aug 2021
Consensus-Based Recommendations for Titrating Cannabinoids and Tapering Opioids for Chronic Pain Control.
Opioid misuse and overuse have contributed to a widespread overdose crisis and many patients and physicians are considering medical cannabis to support opioid tapering and chronic pain control. Using a five-step modified Delphi process, we aimed to develop consensus-based recommendations on: 1) when and how to safely initiate and titrate cannabinoids in the presence of opioids, 2) when and how to safely taper opioids in the presence of cannabinoids and 3) how to monitor patients and evaluate outcomes when treating with opioids and cannabinoids. ⋯ This five-stage modified Delphi process led to the development of consensus-based recommendations surrounding the safe introduction and titration of cannabinoids in concert with tapering opioids.
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Int. J. Clin. Pract. · Aug 2021
Urination behaviors of senior citizens in five Chinese cities: results of a cross-sectional survey.
To investigate the urination behaviours of senior citizens in China. ⋯ Unhealthy urination behaviours, including urinating at night and holding back urine, were common among senior citizens. This result can provide information for the prevention and control of urinary system diseases.