International journal of clinical practice
-
Int. J. Clin. Pract. · Jan 2022
Review Meta AnalysisPrenatal Alcohol Exposure and the Risk of Depression in Offspring: a Meta-Analysis.
Prenatal alcohol exposure (PAE) has been related to poor consequences of mental health in offspring. However, it remains unknown whether maternal alcohol drinking during pregnancy is associated with depression in the offspring. ⋯ Current evidence suggests that PAE may be a risk factor of depression in offspring.
-
Int. J. Clin. Pract. · Jan 2022
Review Meta AnalysisAngiotensin Receptor Blocker is Associated with a Lower Fracture Risk: An Updated Systematic Review and Meta-Analysis.
Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are widely used in the treatment of hypertension. Hypertension is often accompanied by osteoporosis. However, the relationship between ACEI/ARB and fractures remains controversial. The purpose of this meta-analysis was to update the potential relationship between ACEI/ARB and fractures. ⋯ ACEI usage will not decrease the risk of osteoporosis fracture. On the contrary, ARB usage can decrease the risk of total fracture and hip fracture, especially for males and Europeans. Compared with ACEI, for patients at higher risk of fracture in cardiovascular diseases such as hypertension, the protective effect of ARB should be considered.
-
Int. J. Clin. Pract. · Jan 2022
Review Meta AnalysisEfficacy of ω-3 Polyunsaturated Fatty Acids in Patients with Lung Cancer Undergoing Radiotherapy and Chemotherapy: A Meta-Analysis.
Radiotherapy and chemotherapy in patients with lung cancer can lead to a series of problems such as malnutrition and inflammatory reaction. Some studies have shown that ω-3 polyunsaturated fatty acids (PUFAs) could improve malnutrition and regulate inflammatory reaction in these patients, but no relevant meta-analysis exists. ⋯ ω-3 PUFAs can improve nutritional status and regulate indicators of inflammation in patients with lung cancer undergoing radiotherapy and chemotherapy. This study was registered in the PROSPERO (registration number: CRD42022307699).
-
Int. J. Clin. Pract. · Jan 2022
Review Meta AnalysisDietary Inflammatory Index in relation to Type 2 Diabetes: A Meta-Analysis.
Epidemiologic studies show a strong association between chronic inflammation and type 2 diabetes (T2D). Diet may also affect the risk of T2D by modulating inflammation. This meta-analysis aimed to assess the relation of dietary inflammatory index (DII) and risk of T2D. ⋯ Higher DII might be associated with an increased risk of T2D. Additional well-designed studies are required to confirm this finding.
-
Int. J. Clin. Pract. · Jan 2022
Review Meta AnalysisInfluence of Iguratimod on Bone Metabolism in Patients with Rheumatoid Arthritis: A Meta-analysis.
Influence of iguratimod on bone mineral density (BMD) and biomarkers of bone metabolism in patients with rheumatoid arthritis (RA) remains not determined. Accordingly, a meta-analysis was performed for systematical evaluation. ⋯ Iguratimod could prevent the bone loss and improve the bone metabolism in patients with RA.