International journal of clinical practice
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Int. J. Clin. Pract. · Apr 2021
Letter Randomized Controlled TrialEffect of ranolazine as add-on therapy in type 2 diabetic dyslipidaemia patients: A randomised open-label trial.
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Int. J. Clin. Pract. · Apr 2021
Randomized Controlled TrialComparison of insulin degludec (IDeg)/insulin Aspart (IAsp) co-formulation therapy twice-daily with free combination of GLP-1 receptor agonist liraglutide plus insulin degludec in Tochigi: IDEAL Trial.
We compared the efficacy and safety of insulin degludec/insulin aspart co-formulation (IDegAsp) twice-daily to a free combination of basal insulin degludec and GLP-1 receptor agonist liraglutide (IDeg + Lira) once-daily for patients with inadequately controlled type 2 diabetes on insulin therapy and oral antidiabetic drugs. ⋯ In patients with inadequately controlled type 2 diabetes on insulin therapy and oral antidiabetic drugs, treatment with the once-daily dual injection of IDeg + Lira compared with the twice-daily single injection of IDegAsp showed no significant difference in glycaemic control but statistically superior weight loss.
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Int. J. Clin. Pract. · Apr 2021
Randomized Controlled TrialComparison of pain, quality of life, lower urinary tract symptoms and sexual function between flexible and rigid cystoscopy in follow-up male patients with non muscle invasive bladder cancer: a randomized controlled cross section single blind study.
To compare pain, quality of life (QoL), sexual function and lower urinary tract symptoms (LUTS) between rigid (RC) and flexible cystoscopy (FC). ⋯ The results showed that the effects on pain, sexual function, QoL and LUTS of RC and FC were similar. In general, cystoscopy did not affect negatively on QoL, sexual function and LUTS of the patients.
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Int. J. Clin. Pract. · Apr 2021
Randomized Controlled TrialEffects of Perioperative Comprehensive Nursing Based on Risk Prevention for Patients with Intracranial Aneurysm.
To explore the effect of comprehensive nursing based on risk prevention in perioperative nursing of intracranial aneurysm. ⋯ Comprehensive nursing was associated with the shortness of hospitalisation time of patients, improved rescue rate, reduced occurrence of complications and infection, and improved satisfaction of patients. Thus, comprehensive nursing was regarded to exert protective effect with a promising future for clinical practice.
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Int. J. Clin. Pract. · Apr 2021
Randomized Controlled TrialThe Relationship between Depression and Metabolic Control Parameters in Type 2 Diabetic Patients: A Cross-sectional and Feasibility Interventional Study.
Substantial evidence supports a bidirectional relationship between diabetes and clinical depression. However, little is known about the effect of treating one condition on the control of the other. Thus, this study aimed to determine the prevalence of depression among Type II diabetes mellitus (T2DM) patients and to assess the efficacy and feasibility of escitalopram treatment of depression on their metabolic control parameters. ⋯ The relationship between depression and T2DM in the context of metabolic syndrome is plausible. However, our results show that escitalopram treatment may not be associated with significant improvement in metabolic control parameters among these patients. Our study has laid the groundwork for future randomised clinical trials with larger sample size and longer follow-up.