International journal of clinical practice
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Int. J. Clin. Pract. · Apr 2021
Randomized Controlled TrialEffect of hearing aids on attention, memory, and auditory evoked potentials: a pragmatic, single-blinded, and randomized pilot clinical trial.
To compare the effects of hearing aids and their technology levels (premium and basic) on attention, memory, brain response, and self-perceived benefit amongst individuals who were naïve to sound amplification. ⋯ In this study, premium and basic hearing aids impacted attention, memory, brain response, and self-perceived benefit similarly amongst individuals who were naïve to sound amplification after 12 weeks of using the hearing devices.
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Int. J. Clin. Pract. · Apr 2021
Randomized Controlled TrialLung deposition and systemic bioavailability of dose delivered to smoker compared to non-smoker COPD subjects.
Inhaled drugs are the most commonly used class of medications for COPD subjects. No studies have been performed to assess the influence of smoking on lung deposition of aerosolized medication, especially for the exacerbated COPD subject. The present study aimed to assess the influence of smoking on the lung deposition of the aerosol delivered to exacerbated COPD subjects. ⋯ The study demonstrated that smoking reduced the lung deposition of inhaled salbutamol delivered by nebulizer or pMDI. However, the smoking effect on cytochrome p450 was observed to increase systemic absorption of the ingested portion of the inhaled dose. The lower lung deposition and possible higher systemic absorption should be taken into consideration while prescribing inhaled medication to COPD smokers especially exacerbated patients that need ventilation. Further studies are needed.
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Int. J. Clin. Pract. · Mar 2021
Randomized Controlled TrialComparison of External Jugular Vein based surface landmark approach and Ultrasound guided approach for Internal Jugular Venous cannulation: A randomized cross over clinical trial.
Historically, landmark techniques for central venous access through the internal jugular vein (IJV) have yielded a lesser success rate and higher complication rate than the ultrasound (US)-guided approach. The purpose of this study is to assess the success and safety of a novel external jugular vein (EJV)-based landmark (EJV-LM) approach compared with the real-time US-guided approach for central venous access through the IJV. ⋯ In patients with non-distorted neck anatomy and a visible EJV, IJV catheterisation using the EJV-based LM approach and standard US-guided technique yielded similar first-attempt and overall success rates. Cannulation time was longer and complications occurred more frequently in the EJV-based LM compared with the standard US-guided technique.
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Int. J. Clin. Pract. · Mar 2021
Randomized Controlled TrialErector spinae plane block vs. Nonsteroidal anti-inflammatory drugs for severe renal colic pain: a pilot clinical feasibility study.
Ultrasound-guided plane blocks are increasingly used in the multi-modal analgesic concept for reducing opioid consumption. The present study was conducted to compare the analgesic effect of intravenous non-steroidal anti-inflammatory drugs (NSAIDs) and erector spinae plane (ESP) block in renal colic patients. ⋯ ESP block can be an alternative, efficient and safe method for the relief of acute renal colic pain.
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Int. J. Clin. Pract. · Feb 2021
Randomized Controlled Trial Observational StudyAn exploratory randomized controlled trial evaluating text prompts in Lebanon to encourage health-seeking behavior for hypertension.
The current study evaluates the effectiveness of an opportunistic mobile screening on the percentage of people who are aware of whether they may be hypertensive (in an observational study) and the effectiveness of reminder prompts on the percentage of people who seek further medical attention (in a randomised controlled trial). ⋯ Extra support in the form of a brief reminder message can increase the percentage of people who seek further medical attention after attending an opportunistic screening at a marathon event. The discussion reviews how the results align with previous research, strengths and limitations of the current study, and implications for future research and practice.