International journal of clinical practice
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Int. J. Clin. Pract. · Nov 2021
Meta AnalysisThe association between apolipoprotein A-1 plasma level and premature coronary artery disease; a systematic review and meta-analysis.
Apolipoprotein A-1 (Apo A-1) is a constituent of high-density lipoprotein (HDL) and emerging evidences put forward a potential association between Apo A-1 plasma levels and premature coronary artery disease (pCAD). The aim of the present study is to gather relative literature and perform a systematic review and meta-analysis regarding the association between serum ApoA-1 levels and pCAD. ⋯ In conclusion, there seems to be a significant association between the serum levels of ApoA-1 and pCAD. However, all of the included studies had a case-control design and since there is no good quality and prospective cohort studies included, reliability of the current evidence is debatable. Therefore, further well-designed cohort studies are required to assess the impact of serum ApoA-1 reduction on pCAD onset.
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Int. J. Clin. Pract. · Nov 2021
Meta AnalysisThe Effects of Pharmacological Interventions on Smoking Cessation in People with Alcohol Dependence: A Systematic Review and Meta-analysis of Nine Randomized Controlled Trials.
Pharmacotherapies are widely used for smoking cessation. However, their efficacy for people with alcohol dependence remains unclear. ⋯ Varenicline may promote smoking cessation in people with alcohol dependence. However, Naltrexone, Topiramate and Bupropion have no clear effect on increasing smoking abstinence among drinkers. The small number of studies and the low certainty of evidence indicate that the results should be interpreted cautiously.
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Int. J. Clin. Pract. · Nov 2021
Meta AnalysisThe association between psoriasis and psoriatic arthritis with the risk of osteoporosis, osteopenia, and bone fractures: a systematic review and meta-analysis.
The possible association between psoriatic/psoriatic arthritis (PsA) and bone loss has been observed; however, studies have yielded inconclusive results. This meta-analysis aimed to assess whether there is an increase in the risk of osteoporosis, osteopenia and fractures in patients with psoriasis/PsA, compared with healthy individuals. ⋯ Patients with psoriasis/PsA have an increased risk of fractures. There is little evidence supporting the relation of psoriasis to osteoporosis/osteopenia.
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Int. J. Clin. Pract. · Nov 2021
Meta AnalysisComparison of efficacy and safety of gabapentin and duloxetine in painful diabetic peripheral neuropathy: A systematic review and meta-analysis of randomized controlled trials.
In patients with diabetes mellitus, painful diabetic peripheral neuropathy (PDPN) is a frequent complication and can cause poor quality of life. We compared the efficacy and safety of duloxetine with those of gabapentin in patients with PDPN through a systematic review and meta-analysis of randomised controlled trials. ⋯ No significant differences were observed in the efficacy of duloxetine and gabapentin when treating patients with PDPN.
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Int. J. Clin. Pract. · Nov 2021
ReviewThe Impact of Pharmacy Care and Motivational Interviewing on improving medication adherence in patients with cardiovascular diseases: A Systematic Review of Randomised Controlled Trials.
Cardiovascular disease (CVD) is prevalent worldwide, and for many patients, non-adherence to medication remains a problem. Motivational interviewing is a behavioural, communication strategy used as an intervention aimed to improve health outcomes. ⋯ Motivational interviewing could be an effective behavioural strategy to enhance medication adherence in patients with CVD. Although the evidence is promising thus far, further research is required to explore the impact of motivational interviewing on clinical outcomes as well as the feasibility of implementing motivational interviewing interventions within existing pharmacy care services.