International journal of clinical practice
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Int. J. Clin. Pract. · Nov 2021
Randomized Controlled TrialRifaximin microbial resistance and its efficacy and safety as a secondary prophylaxis of hepatic encephalopathy in patients with HCV related cirrhosis.
Rifaximin is an oral antibiotic with promising efficacy in the reduction of hepatic encephalopathy (HE) recurrence. Development of microbial resistance to rifaximin is not studied yet in HE. The study aim was to assess the microbial resistance, safety and efficacy of rifaximin as secondary prophylaxis of HE. ⋯ Rifaximin succeeded to maintain remission from new episodes of HE in hepatitis C virus cirrhotic patients with limited potential for development of microbial resistance over the study period. ClinicalTrials.gov Identifier: NCT04736836.
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Int. J. Clin. Pract. · Nov 2021
Psychological problems among the university students in Saudi Arabia during the COVID-19 pandemic.
The 2019 coronavirus disease (COVID-19) pandemic is a public health emergency that represents a challenge to psychological health. This study aimed to assess the psychological conditions among university students in Saudi Arabia during the COVID-19 pandemic. ⋯ Symptoms of depression, anxiety, and stress were common among Saudi university students during the COVID-19 pandemic. Psychological counselling and support should be provided to university students in Saudi Arabia.
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Int. J. Clin. Pract. · Nov 2021
Meta AnalysisEffect of Artemisia extract on glycemic control: A systematic review and meta-analysis of randomized controlled trial.
Animal and human studies have indicated anti-diabetic effect of Asteraceae. The present study aimed to systematically review and analyse randomized controlled trials assessing the effect of Artemisia extract on glycemic status in patients with impaired glycemic control. ⋯ Supplementation with Artemisia extract may reduce HOMA-IR, but beneficial effects on other markers such as FBG requires further investigations.
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Int. J. Clin. Pract. · Nov 2021
Letter Review Meta AnalysisPrevalence of comorbid tuberculosis amongst COVID-19 patients: A rapid review and meta-analysis.
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Int. J. Clin. Pract. · Nov 2021
Impact of pharmacist-led interventions on patient care in ambulatory care settings: A systematic review.
In an era of rapid evolution in healthcare delivery, major changes have occurred within the profession of pharmacist. Because the impact of pharmacist-led interventions in the hospital setting has been well-studied and showed mixed findings on drug-related readmissions, all-cause emergency department visits and mortality, this systematic review focused on services provided by pharmacists in the community or ambulatory care setting without being limited to a specific intervention or outcome. ⋯ Our results showed that CMR can play a major role in the management of drug-related problems and economic issues. AR can significantly improve patient compliance. Larger, standardised and rigorously designed intervention studies are needed to help decision-makers to select appropriate interventions leading to meaningful improvements in patient care.