Pulmonary pharmacology & therapeutics
-
Pulm Pharmacol Ther · Feb 2014
Meta AnalysisEfficacy and safety of roflumilast in patients with stable chronic obstructive pulmonary disease: a meta-analysis.
Currently, several large studies showed that roflumilast has been demonstrated efficacy during treatment chronic obstructive pulmonary disease (COPD) patients, but also caused some side effects. ⋯ Roflumilast significantly reduces the mean exacerbation rate in COPD patients. Although there are insufficient clinical evidence on other clinical endpoints and high risk of some adverse events, roflumilast therapy may benefit COPD patients. Further studies are needed to pay more attention to the long-term efficacy and safety of roflumilast.