Current opinion in organ transplantation
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Curr Opin Organ Transplant · Dec 2011
ReviewTransplantation of the broadly sensitized patient: what are the options?
Recipient sensitization to a wide variety of human leukocyte antigens (HLA) represents a major barrier to transplantation. We discuss the options for the challenging group of broadly sensitized kidney transplant candidates. ⋯ A multifaceted repertoire of complementary strategies was shown to facilitate successful live and deceased donor kidney transplantation in high-risk patients. Recent promising developments can be expected to significantly improve outcomes.