Current opinion in organ transplantation
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Curr Opin Organ Transplant · Jun 2013
ReviewResults of pretransplant treatment of hepatorenal syndrome with terlipressin.
Hepatorenal syndrome (HRS) is a dreaded complication of end-stage liver disease. The best treatment option for HRS is liver transplantation (LT) in suitable candidates. Pretransplant care of HRS is of utmost importance in order to secure a good posttransplant outcome. We review the advances during the last year in the diagnosis and management of HRS in candidates who are awaiting liver transplantation. ⋯ Ongoing advances in the management of patients with HRS before liver transplantation indicate that vasoconstrictors plus albumin should be offered to all suitable candidates. Liver transplantation remains the best treatment option for HRS.
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Curr Opin Organ Transplant · Jun 2013
ReviewEvolving aspects of liver transplantation for nonalcoholic steatohepatitis.
Nonalcoholic steatohepatitis (NASH), obesity, and the metabolic syndrome are highly prevalent. NASH, a rare indication for liver transplantation in the early 1990s, is now the third most common indication. This review considers key aspects of the liver transplantation for NASH. ⋯ A nuanced approach is needed in management of obesity, metabolic syndrome, and immunosuppression in liver transplant recipients.