The British journal of surgery
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Comparative Study
Local resection or pancreaticoduodenectomy for villous adenoma of the ampulla of Vater diagnosed before operation.
Treatment of ampullary adenoma is complicated by difficult preoperative staging, malignant potential and a high recurrence rate. This study was designed to assess the accuracy of diagnosis and staging by endoscopic biopsy and endosonography, and to compare the results of local resection and pancreaticoduodenectomy (Whipple procedure). ⋯ Diagnosis and staging of ampullary adenomas by endoscopic biopsy and endosonography was unreliable. Local resection seems a viable alternative for patients whose general condition does not allow a Whipple procedure.
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Comment Letter Randomized Controlled Trial Clinical Trial
Prospective randomized trial of clips versus subcuticular polydioxanone for neck wound closure.
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Erythromycin has been shown to be a powerful prokinetic of the gastrointestinal tract. Little is known about its value to improve motility and transit in gastrectomized patients. ⋯ Oral erythromycin improves gastrointestinal transit and motility after subtotal gastrectomy. The findings after total gastrectomy are controversial.