The British journal of surgery
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Randomized Controlled Trial Comparative Study
Randomized clinical trial of concomitant or sequential phlebectomy after endovenous laser therapy for varicose veins.
The management of residual varicosities following endovenous laser therapy (EVLT) for varicose veins is contentious. Ambulatory phlebectomy may be performed concomitantly with the initial EVLT, or sequentially as a secondary procedure. This randomized trial compared these two approaches. ⋯ Concomitant phlebectomy with EVLT prolonged the procedure, but reduced the need for secondary procedures and significantly improved quality of life and the severity of venous disease.
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Randomized Controlled Trial Comparative Study
Randomized clinical trial of Entonox versus midazolam-fentanyl sedation for colonoscopy.
Intravenous sedation for colonoscopy is associated with cardiorespiratory complications and delayed recovery. The aim of this randomized clinical trial was to compare the efficacy of Entonox (50 per cent nitrous oxide and 50 per cent oxygen) and intravenous sedation using midazolam-fentanyl for colonoscopy. ⋯ Entonox provides better pain relief and faster recovery than midazolam-fentanyl and so is more effective for colonoscopy.