The British journal of surgery
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Multicenter Study Controlled Clinical Trial
Multicentre trial of a perioperative protocol to reduce mortality in patients with peptic ulcer perforation.
Morbidity and mortality rates in patients with perforated peptic ulcer (PPU) remain substantial. The aim of the present study was to evaluate the effect of a multimodal and multidisciplinary perioperative care protocol on mortality in patients with PPU. ⋯ NCT00624169 (http://www.clinicaltrials.gov).