The British journal of surgery
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Randomized Controlled Trial Multicenter Study
Randomized clinical trial of ischaemic preconditioning in major liver resection with intermittent Pringle manoeuvre.
Vascular inflow occlusion is effective in avoiding excessive blood loss during hepatic parenchymal transection but may cause ischaemic damage to the remnant liver. Intermittent portal triad clamping (IPTC) is superior to continuous hepatic pedicle clamping as it avoids severe ischaemia-reperfusion (IR) injury in the liver remnant. Ischaemic preconditioning (IPC) before continuous Pringle manoeuvre may protect against IR during major liver resection. ⋯ NCT00908245 (http://www.clinicaltrials.gov).
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Randomized Controlled Trial Multicenter Study Comparative Study
Randomized clinical trial of tissue glue versus absorbable sutures for mesh fixation in local anaesthetic Lichtenstein hernia repair.
Chronic pain may be a long-term problem related to mesh fixation and operative trauma after Lichtenstein hernioplasty. The aim of this study was to compare the feasibility and safety of tissue cyanoacrylate glue versus absorbable sutures for mesh fixation in Lichtenstein hernioplasty. ⋯ NCT00659542 (http://www.clinicaltrials.gov).