The British journal of surgery
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Multicenter Study Observational Study
Multicentre international trial of laparoscopic lavage for Hinchey III acute diverticulitis (LLO Study).
Laparoscopic lavage was proposed in the 1990s to treat purulent peritonitis in patients with perforated acute diverticulitis. Prospective randomized trials had mixed results. The aim of this study was to determine the success rate of laparoscopic lavage in sepsis control and to identify a group of patients that could potentially benefit from this treatment. ⋯ Laparoscopic lavage showed a high rate of successful sepsis control in selected patients with perforated Hinchey III acute diverticulitis affected by peritonitis, with low rates of operative mortality, reoperation and stoma formation.
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Multicenter Study Observational Study
Current practice and short-term outcomes of therapeutic mammaplasty in the international TeaM multicentre prospective cohort study.
Therapeutic mammaplasty, which combines breast reduction and mastopexy techniques with tumour excision, may extend the boundaries of breast-conserving surgery and improve outcomes for patients, but current practice is unknown and high-quality outcome data are lacking. This prospective multicentre cohort study aimed to explore the practice and short-term outcomes of the technique. ⋯ Therapeutic mammaplasty is a safe and effective alternative to mastectomy or standard breast-conserving surgery. Further work is required to explore the impact of the technique on quality of life, and to establish cost-effectiveness.
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Multicenter Study
CCR-CARESS score for predicting operative mortality in patients with colorectal cancer.
The aim of this study was to assess factors associated with outcomes after surgery for colorectal cancer and to design and internally validate a simple score for predicting perioperative mortality. ⋯ Elderly patients with co-morbidity and palliative intention of surgery have an unacceptably high risk of death.