The British journal of surgery
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The optimal prognostic markers for neoadjuvant chemotherapy in patients with borderline resectable or locally advanced pancreatic cancer are not yet established. ⋯ Reduction in metabolic tumour parameters of FDG- PET/CT after neoadjuvant chemotherapy indicates improved overall survival and recurrence-free survival.
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Meta Analysis Comparative Study
Neoadjuvant therapy versus direct to surgery for T4 colon cancer: meta-analysis.
Despite persistently poor oncological outcomes, approaches to the management of T4 colonic cancer remain variable, with the role of neoadjuvant therapy unclear. The aim of this review was to compare oncological outcomes between direct-to-surgery and neoadjuvant therapy approaches to T4 colon cancer. ⋯ Compared with direct to surgery, neoadjuvant therapy improves margin-negative resection rates and overall survival.