Critical care : the official journal of the Critical Care Forum
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Letter Meta Analysis
Efficacy of tocilizumab treatment in severely ill COVID-19 patients.
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In-hospital cardiac arrest (IHCA) is a major adverse event with a high mortality rate if not treated appropriately. Extracorporeal cardiopulmonary resuscitation (ECPR), as adjunct to conventional cardiopulmonary resuscitation (CCPR), is a promising technique for IHCA treatment. Evidence pertaining to neurological outcomes after ECPR is still scarce. ⋯ ECPR as treatment for in-hospital cardiac arrest is associated with a large proportion of patients with good neurological outcome. The large proportion of favourable outcome could potentially be explained by the selection of patients for treatment using ECPR. Moreover, survival is higher than described in the conventional CPR literature. As indications for ECPR might extend to older or more fragile patient populations in the future, research should focus on increasing survival, while maintaining optimal neurological outcome.
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Meta Analysis
Timing of norepinephrine initiation in patients with septic shock: a systematic review and meta-analysis.
Early initiation of norepinephrine infusion in septic shock is associated with decreased short-term mortality.
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