Pediatric transplantation
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Pediatric transplantation · Sep 2016
ReviewLiver transplantation for pediatric inherited metabolic disorders: Considerations for indications, complications, and perioperative management.
LT is an effective therapeutic option for a variety of IEM. This approach can significantly improve the quality of life of patients who suffer from severe disease manifestations and/or life-threatening metabolic decompensations despite medical/dietary management. ⋯ Successful liver transplant for these complex disorders can be achieved with disease- and patient-specific strategies using a multidisciplinary approach. In this article, we review indications, complications, perioperative management, and long-term follow-up recommendations for IEM that are treatable with LT.