Neuromodulation : journal of the International Neuromodulation Society
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Randomized Controlled Trial
Noninvasive Transcutaneous Vagus Nerve Stimulation Decreases Whole Blood Culture-Derived Cytokines and Chemokines: A Randomized, Blinded, Healthy Control Pilot Trial.
The purpose of this study was to test the transcutaneous noninvasive vagus nerve stimulator (nVNS) (gammaCore©) device to determine if it modulates the peripheral immune system, as has been previously published for implanted vagus nerve stimulators. ⋯ nVNS downregulates inflammatory cytokine release suggesting that nVNS may be an effective anti-inflammatory treatment.