Regional anesthesia and pain medicine
The most recent articles from:
Reg Anesth Pain Med
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Reg Anesth Pain Med · Aug 2019
Perioperative duloxetine for acute postoperative analgesia: a meta-analysis of randomized trials.
Multimodal analgesia is a fundamental part of modern surgery and enhanced recovery pathways. Duloxetine, a serotonin and norepinephrine reuptake inhibitor, has been validated for the treatment of chronic neuropathic pain. The evidence for duloxetine as an adjunct for the treatment of acute postoperative pain remains controversial. We conducted a meta-analysis to determine the efficacy of duloxetine in the acute perioperative setting. ⋯ CRD42019121416.