Regional anesthesia and pain medicine
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Reg Anesth Pain Med · May 1999
Comparative StudyPreemptive intrathecal ketamine injection produces a long-lasting decrease in neuropathic pain behaviors in a rat model.
Ketamine is an N-Methyl-D-Aspartate (NMDA) receptor antagonist, which has been found to effectively treat somatic and neuropathic pain. This study examines the effect (on neuropathic pain) of preemptive ketamine using different routes of administration (intrathecal versus intraperitoneal). ⋯ Neuropathic pain behaviors were significantly reduced for at least 2 weeks after intrathecal ketamine was preemptively administered to animals undergoing surgery to induce neuropathic pain. The mechanism of action is thought to be prevention of spinal cord sensitization.
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Reg Anesth Pain Med · May 1999
Case ReportsAxillary block complicated by hematoma and radial nerve injury.
Hematoma is typically cited as one mechanism of nerve injury following axillary block. However, documented cases of this are lacking. ⋯ Hematoma complicating axillary block may result in nerve dysfunction.
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Reg Anesth Pain Med · May 1999
Biography Historical ArticleRalph Waters as a regional anesthesiologist.
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Reg Anesth Pain Med · May 1999
Biography Historical ArticleDonald Bruce Scott, M.D., F.R.C.A., F.R.D.P.Ed. 1925-1998.