Regional anesthesia and pain medicine
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Reg Anesth Pain Med · Nov 2006
Randomized Controlled TrialEffects of intrathecal midazolam on postoperative analgesia when added to a bupivacaine-clonidine mixture.
Previous clinical and experimental studies have shown that a midazolam-clonidine mixture has a synergistic antinociceptive effect. This study evaluated the postoperative analgesic effect of adding midazolam to an intrathecal bupivacaine-clonidine mixture. ⋯ Addition of midazolam to an intrathecal B-C mixture does not potentiate postoperative analgesia but prolongs the motor blockade.
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Reg Anesth Pain Med · Nov 2006
Clinical TrialIncrease in skin temperature after spinal anesthesia in infants.
The relatively stable hemodynamics during spinal anesthesia in infants have been attributed to a less active sympathetic nervous system in comparison with adults. Thus, the authors evaluated sympathetic block primarily by measurement of skin temperature and secondarily by determination of noninvasive blood pressure as an indirect sign of sympatholysis. ⋯ The authors found a significant increase in skin temperature of the feet within 10 minutes as a sign of sympatholysis, whereas trunk temperature remained constant. Blood pressure decreased but remained within the normal range, despite the observed sympatholysis.
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Reg Anesth Pain Med · Nov 2006
Historical ArticleRegional anesthesia and pain medicine after 30 years: A historical perspective.
Regional Anesthesia and Pain Medicine celebrates its 30th anniversary in 2006. What began as a 10-page, industry-sponsored bulletin has evolved into a major anesthesiology and pain journal. This history article chronicles the journal's growth and development over 3 decades.
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Reg Anesth Pain Med · Nov 2006
Detection of epithelial cell transfer in spinal areas by light microscopy and determining any tissue coring via cell culture during combined spinal-epidural interventions.
Epithelial tissue coring by spinal needles during subarachnoid injections may cause intraspinal epidermal tumors. Previous studies have investigated tissue transfer with different needle types during subarachnoid or epidural injection. This study deals with the transfer of epithelial tissue during combined spinal-epidural (CSE) anesthesia. ⋯ We could not reproduce the cells or cell debris obtained during the CSE interventions in vivo, which can be explained by a possible structural deformation of cells or the inadequacy of the amount of cells that were transferred.