Regional anesthesia and pain medicine
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Reg Anesth Pain Med · May 2019
Medial branch radiofrequency ablation outcomes in patients with centralized pain.
We hypothesized that patients with characteristics of centralized pain (fibromyalgia (FM)-like phenotype) would be less likely to respond to radiofrequency ablation (RFA), which may explain some of the failures of this peripherally directed therapy. ⋯ Although patients with high baseline centralized pain exhibited less improvement in overall pain, this trend was not statistically significant, possibly due to insufficient power. The same trend was not seen with change in spine pain with both groups improving equally. Centralized pain patients may have less improvement in overall pain but may have equal improvement in their site-specific pain levels after localized interventions.
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Reg Anesth Pain Med · May 2019
Ultrasound therapy reduces persistent post-thoracotomy tactile allodynia and spinal substance P expression in rats.
Therapeutic ultrasound (TU) alleviates nerve injury-associated pain, while the molecular mechanisms are less clear. This is an investigator-initiated experimental study to evaluate the mechanisms and effects of ultrasound on prolonged post-thoracotomy pain in a rodent model. ⋯ The results of this study suggest an increase in mechanical withdrawal thresholds and subcutaneous temperature, as well as a downregulation of spinal substance P and IL-1β, in the group which received ultrasound treatment. The regulation of spinal substance P and IL-1β may mediate potential effects of this non-invasive treatment.
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Reg Anesth Pain Med · May 2019
Retraction Of PublicationRetraction: Pericapsular nerve group block: an ethical and academic etiquette perspective.