Regional anesthesia and pain medicine
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Reg Anesth Pain Med · Nov 1998
Randomized Controlled Trial Clinical TrialLocal anesthetic effect of tramadol, metoclopramide, and lidocaine following intradermal injection.
We observed clinically that tramadol and metoclopramide appear to have local anesthetic action. Tramadol is a central-acting analgesic. Metoclopramide is a commonly used antiemetic. The local anesthetic effect of tramadol in reducing propofol injection pain has never been mentioned, although it was speculated with metoclopramide. ⋯ Intradermal tramadol or metoclopramide can produce local anesthetic effect.
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Reg Anesth Pain Med · Nov 1998
Randomized Controlled Trial Comparative Study Clinical TrialPostoperative analgesia in children using preemptive retrobulbar block and local anesthetic infiltration in strabismus surgery.
Postoperative pain management in pediatric strabismus patients is infrequently studied. Pediatric patients can be mobilized earlier if postoperative pain is minimized. In this study, two different regional anesthetic techniques, retrobulbar block and local infiltration, were compared with a "no block" control group for the postoperative management of pain in pediatric patients undergoing elective strabismus surgery. ⋯ Because there was no significant difference in terms of postoperative analgesia in the retrobulbar block or subconjunctival local anesthetic infiltration groups compared with the control group, we suggest that conventional methods of pain treatment are adequate for postoperative analgesia in strabismus surgery.
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Reg Anesth Pain Med · Nov 1998
Randomized Controlled Trial Clinical TrialPre-incision infiltration with lidocaine reduces pain and opioid consumption after reduction mammoplasty.
To determine the analgesic efficacy of preoperative tumescent infiltration with lidocaine for reduction mammoplasty. ⋯ Preoperative tumescent infiltration with lidocaine results in reduced pain and lower postoperative opioid requirements in the initial hours after reduction mammoplasty.
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Reg Anesth Pain Med · Nov 1998
Randomized Controlled Trial Comparative Study Clinical TrialClonidine added to bupivacaine-epinephrine-sufentanil improves epidural analgesia during childbirth.
A double-blind study was conducted to assess the efficacy and the side effects of a low dose of clonidine added to an epidural injection of bupivacaine and epinephrine, with or without sufentanil. ⋯ The addition of a low dose of clonidine to an epidural injection of bupivacaine with epinephrine and sufentanil provides better analgesia during labor, while keeping the side effects minimal and of minor clinical importance.
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Reg Anesth Pain Med · Sep 1998
Randomized Controlled Trial Clinical TrialIntrathecal sufentanil and epidural bupivacaine for labor analgesia: dose-response of individual agents and in combination.
Combinations of local anesthetics and opioids are frequently used during spinal and epidural analgesia for the relief of labor pain. This combination allows for a dose-sparing effect which may reduce potential side effects or toxicity. The precise nature of the interaction between opioids and local anesthetics in the clinical setting, i.e., additivity versus synergism, has not been established. This trial was designed to utilize a validated technique of analysis of drug interactions, isobolography, to investigate this interaction. ⋯ Markedly reduced doses of these drugs in combination can be used to provide adequate analgesia during labor compared with either single drug alone.