Regional anesthesia and pain medicine
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Reg Anesth Pain Med · Jul 2010
The anatomy of the thoracic spinal canal in different postures: a magnetic resonance imaging investigation.
The goal of this study was to investigate,with magnetic resonance imaging, the human anatomic positions of the spinal canal (eg, spinal cord, thecal tissue) in various postures and identify possible implications from different patient positioning for neuraxial anesthetic practice. ⋯ The spinal cord follows the straightest line through the imposed geometry of the spinal canal. Accordingly, there is relatively more posterior separation of the cord and surrounding thecal tissue at midthoracic levels in the apex of the thoracic kyphosis. Placing a patient in a position that accentuates the thoracic curvature of the spine (ie,sitting head-down) increases the posterior separation of the spinal cord and dural sheath at thoracic levels.
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Reg Anesth Pain Med · Jul 2010
Comparative StudyThe effect of fluid injection on lesion size during radiofrequency treatment.
Previous ex vivo studies on monopolar radiofrequency have not incorporated the preinjection of fluid before radiofrequency ablation into study design. The objective of this study was to investigate the effects of the preinjection of small volumes of different fluids on lesion dimensions. ⋯ The influence of the composition of the pre-injected fluid should be considered for monopolar radiofrequency ablation. This ex vivo study revealed a simple method to increase monopolar radiofrequency lesion size. Future research is needed to determine the degree of influence of the composition of the fluid on thermal and electrical conductivity.
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Reg Anesth Pain Med · Jul 2010
Randomized Controlled Trial Comparative StudyProtein balance in nondiabetic versus diabetic patients undergoing colon surgery: effect of epidural analgesia and amino acids.
Surgical injury provokes a stress response that is thought to be pronounced in patients with diabetes mellitus type 2 (DM2) leading to intensified catabolism. The aim of this study was to compare the effects of perioperative epidural analgesia (EDA) versus patient controlled analgesia (PCA) and amino acid infusion on postoperative metabolism in patients with and without DM2. ⋯ A short-term infusion of amino acids reduced protein breakdown, increased protein synthesis, and rendered protein balance positive. This anabolic effect was pronounced in diabetic patients with EDA compared with nondiabetic patients or PCA, respectively, and prevented an undesirable hyperglycemia.