Regional anesthesia and pain medicine
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Reg Anesth Pain Med · May 2002
Randomized Controlled Trial Comparative Study Clinical TrialAmethocaine-lidocaine cream, a new topical formulation for preventing venopuncture-induced pain in children.
The aim of this study was to compare the effectiveness of 3 anesthetic creams in relieving venous puncture-related pain in children. ⋯ All 3 creams proved to be effective in relieving venous puncture pain in children. EMLA presented a longer latency period, 4% amethocaine showed the highest percentage of untoward effects, and AMLI exhibited a shorter latency period than EMLA, while having fewer adverse effects than 4% AMET and EMLA.
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Reg Anesth Pain Med · May 2002
Randomized Controlled Trial Clinical TrialAnalgesic effects of dexamethasone in burn injury.
Glucocorticoids are well-known adjuvant analgesics in certain chronic pain states. There is, however, a paucity of data on their analgesic efficacy in acute pain. Therefore, the aim of the study was to examine the analgesic effects of dexamethasone in a validated burn model of acute inflammatory pain in humans. ⋯ The study indicates that systemic administration of dexamethasone 2 hours before a burn injury does not reduce the inflammatory-mediated changes in quantitative sensory thresholds, pain perception, or skin erythema in humans.
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Reg Anesth Pain Med · May 2002
Randomized Controlled Trial Clinical TrialIntrathecal hyperbaric bupivacaine dose response in postpartum tubal ligation patients.
Because of its short duration, hyperbaric lidocaine has been a popular intrathecal drug to provide anesthesia for postpartum tubal ligation (PPTL). However, reports of transient symptoms associated with its use have prompted the search for alternative intrathecal local anesthetics for short procedures. Hyperbaric bupivacaine is rarely associated with transient neurologic symptoms, and we designed this study to determine the optimal dose of bupivacaine for PPTL that assures adequate sensory block and allows the patient the shortest recovery time. ⋯ Hyperbaric bupivacaine 7.5 mg injected in the lateral position provides adequate surgical anesthesia for PPTL with a minimal duration of motor block and recovery time.
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Reg Anesth Pain Med · Mar 2002
Randomized Controlled Trial Comparative Study Clinical TrialContinuous subgluteus sciatic nerve block after orthopedic foot and ankle surgery: comparison of two infusion techniques.
To compare continuous infusion or a patient-controlled technique for postoperative analgesia after foot surgery, using a new subgluteus approach for continuous sciatic nerve block. ⋯ The continuous subgluteus sciatic nerve block represents an easy and reliable option for postoperative analgesia after foot surgery; using a patient controlled rather than a continuous infusion technique reduces the consumption of local anesthetic solution without affecting the quality of pain relief.
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Reg Anesth Pain Med · Mar 2002
Randomized Controlled Trial Clinical TrialBuprenorphine added to the local anesthetic for axillary brachial plexus block prolongs postoperative analgesia.
Buprenorphine added to local anesthetic solutions for supraclavicular block was found to triple postoperative analgesia duration in a previous study when compared with local anesthetic block alone. That study, however, did not control for potentially confounding factors, such as the possibility that buprenorphine was affecting analgesia through intramuscular absorption or via a spinal mechanism. To specifically delineate the role of buprenorphine in peripherally mediated opioid analgesia, the present study controlled for these 2 factors. ⋯ Buprenorphine-local anesthetic axillary perivascular brachial plexus block provided postoperative analgesia lasting 3 times longer than local anesthetic block alone and twice as long as buprenorphine given by IM injection plus local anesthetic-only block. This supports the concept of peripherally mediated opioid analgesia by buprenorphine.