La Clinica terapeutica
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La Clinica terapeutica · Jan 2008
Randomized Controlled Trial[Treatment of mild malnutrition and reduction of morbidity in major abdominal surgery: randomized trial on 153 patients].
Severe malnutrition (defined as weight loss more than 10% in a period of six months) is considered an important risk factor in major abdominal surgery, because of a higher post-operative mortality and morbidity. The aim of our study is to assess the role of mild malnutrition (weight loss low than 10% in a period of six months) as a risk factor in major abdominal surgery and to evaluate the efficacy of therapy in order to improve outcomes in terms of in-hospital mortality, length of hospital stay and post-operative complications. Moreover, we evaluated serum albuminemia and lymphocyte count, important nutritional index, as predictive risk factors. ⋯ Nutritional enriched support demonstrated his efficacy in reducing morbidity, and length of hospital stay. Pre-operative oral immunonutrition might be suggested and established in all the patients with mild malnutrition that will be operated on major abdominal surgery.
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La Clinica terapeutica · Jan 2008
[Sedation with propofol in endoscopic retrograde cholangiopancreatography: personal experience].
Adequate sedation is fundamental for the execution of the endoscopic retrograde cholangiopancreatography (ERCP). Propofol is widely used for gastrointestinal endoscopy because of its rapid recovery profile. The aim of this study was to determine, retrospectively, whether the administration of propofol was safe in patients undergoing ERCP, both diagnostic and therapeutic. ⋯ Propofol seems to be safe and effective sedation for ERCP, with a low complication rate, also in patients aged 80 years or older.