Journal of clinical monitoring and computing
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J Clin Monit Comput · Oct 2023
Quantitative electroencephalogram in term neonates under different sleep states.
Electroencephalogram (EEG) can be used to assess depth of consciousness, but interpreting EEG can be challenging, especially in neonates whose EEG undergo rapid changes during the perinatal course. EEG can be processed into quantitative EEG (QEEG), but limited data exist on the range of QEEG for normal term neonates during wakefulness and sleep, baseline information that would be useful to determine changes during sedation or anesthesia. We aimed to determine the range of QEEG in neonates during awake, active sleep and quiet sleep states, and identified the ones best at discriminating between the three states. ⋯ Entropy beta and SEF50 were best at discriminating between awake and sleep states. QEEG were not as good at discriminating between quiet and active sleep. In the future, QEEG with high discriminatory power can be combined to further improve ability to differentiate between states of consciousness.
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J Clin Monit Comput · Oct 2023
Observational StudyEchocardiographic hemodynamic assessment in decompensated cirrhosis: comparison between Intensivists and Gastroenterologists.
Ascites is a frequent complication of cirrhosis. In intensive care units, initial hemodynamic assessment is frequently performed by echocardiography. This study evaluated the feasibility and usefulness of early hemodynamic assessment in the gastroenterology ward. ⋯ NCT03650660.
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J Clin Monit Comput · Oct 2023
Observational StudyFeasibility analysis of a novel non-invasive ultrasonographic method for the measurement of intra-abdominal pressure in the intensive care unit.
Increased intra-abdominal pressure (IAP) is an important vital sign in critically ill patients and has a negative impact on morbidity and mortality. This study aimed to validate a novel non-invasive ultrasonographic approach to IAP measurement against the gold standard intra-bladder pressure (IBP) method. We conducted a prospective observational study in an adult medical ICU of a university hospital. ⋯ Bland and Altman's analysis showed a bias (0.39 and 0.61 mmHg) and precision (1.38 and 1.51 mmHg) for the comparison of IAPUS1 and IAPUS2 and vs. IBP, respectively with small limits of agreement that were in line with the research guidelines of the Abdominal Compartment Society (WSACS). Our novel ultrasound-based IAP method displayed good correlation and agreement between IAP and IBP at levels up to 15 mmHg and is an excellent solution for quick decision-making in critically ill patients.
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J Clin Monit Comput · Oct 2023
Modeling the impacts of assumptions and nonpulmonary factors on the performance and reliability of indices of oxygenation.
Assessment of oxygenation is fundamental to the care of patients. Numerous indices of oxygenation have been developed that entail variable degrees of invasiveness, complexity and physiologic underpinning. The clinical reliability of these indices has been questioned. ⋯ These effects manifested as calculated indices either over or under-estimating actual shunt by FShunt, or wide unpredictable variability (scatter) when correlating A-a [Formula: see text] gradient and Pa:Fi ratio to actual shunt. Cardiac output and oxygen extraction have noticeable impacts on all calculated indices. The results support the clinical observations that the performance of indices of oxygenation can vary with fraction of inspired oxygen and various nonpulmonary physiological factors that underly heterogeneity present in the clinical population.
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J Clin Monit Comput · Oct 2023
Observational StudyExhaled patient derived aerosol dispersion during awake tracheal intubation with concurrent high flow nasal therapy.
Awake Tracheal Intubation (ATI) can be performed in cases where there is potential for difficult airway management. It is considered an aerosol generating procedure and is a source of concern to healthcare workers due to the risk of transmission of airborne viral infections, such as SARS-CoV-2. At present, there is a lack of data on the quantities, size distributions and spread of aerosol particles generated during such procedures. ⋯ Patient derived aerosol particles < 5 µm in diameter remained entrained in the exhaled aerosol plume and fell to the floor or onto the subject. Patient derived particles > 5 µm in diameter broke away from the exhaled plume and spread radially throughout the operating room. Irrespective of distance and ventilation status, full airborne protective equipment should be worn by all staff when ATI is being performed on patients with suspected viral respiratory infections.