Climacteric : the journal of the International Menopause Society
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Randomized Controlled Trial Comparative Study
Non-hormonal treatment of hot flushes in breast cancer survivors: gabapentin vs. vitamin E.
To assess the efficacy and the tolerability of gabapentin 900 mg/day compared to vitamin E for the control of vasomotor symptoms in 115 women with breast cancer. The secondary objective was to evaluate the effect of the treatments on the quality of sleep and other aspects of the quality of life. ⋯ Gabapentin appears to be effective for the treatment of hot flushes with a favorable effect on quality of sleep. Vitamin E has only marginal effect on vasomotor symptoms.