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Pharmaceutical biology
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Pharmaceutical biology · Aug 2013
Inhibitory effect of liposome-encapsulated anthocyanin on melanogenesis in human melanocytes.
Melanin plays an important role in preventing ultraviolet (UV) light-induced skin damage. Overexposure to UV radiation can lead to the formation of free radicals and trigger inflammation and hyperpigmentation of the skin. Anthocyanin can combat excessive free radicals in the body and can reduce the occurrence of inflammation. However, anthocyanin molecules are unstable and highly susceptible to degradation. ⋯ Liposome encapsulation increases the stabilization of anthocyanin and the inhibition of melanogenesis. Our findings indicate that LCA may be suitable as a photoprotective agent for the skin.