Experimental gerontology
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Experimental gerontology · Dec 2013
Comparative StudySimplified method of clinical phenotyping for older men and women using established field-based measures.
The purpose of this investigation was to determine body composition classification using field-based testing measurements in healthy elderly men and women. The use of isoperformance curves is presented as a method for this determination. Baseline values from 107 healthy Caucasian men and women, over the age of 65years old, who participated in a separate longitudinal study, were used for this investigation. ⋯ Isoperformance curves were developed from the relationship between BMI and handgrip strength for men and women with the aforementioned clinical phenotype classification criteria. These visual representations were used to aid in the classification and evaluation of sarcopenia, obesity, and sarcopenic-obesity in elderly individuals. Future research should replicate the current findings with an increased sample size and the development of tailored interventions for each body composition category.
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Experimental gerontology · Dec 2013
Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults.
Vitamin E includes eight natural antioxidant compounds (four tocopherols and four tocotrienols), but α-tocopherol has been the main focus of investigation in studies of cognitive impairment and Alzheimer's disease. ⋯ Elevated levels of tocopherol and tocotrienol forms are associated with reduced risk of cognitive impairment in older adults. The association is modulated by concurrent cholesterol concentration. Various vitamin E forms might play a role in cognitive impairment, and their evaluation can provide a more accurate measure of vitamin E status in humans.