Experimental gerontology
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Experimental gerontology · Sep 2016
Review Meta AnalysisIs pain sensitivity altered in people with Alzheimer's disease? A systematic review and meta-analysis of experimental pain research.
Clinical studies suggest people with Alzheimer's disease (AD) have altered pain sensitivity. Experimental pain research is equivocal. ⋯ People with AD have a greater sensitivity to pain when validated observer ratings of facial expressions are used. Verbal response to painful stimuli, even under experimental conditions, may mean pain is not identified in people with AD. Clinically useful observer rated pain tools may be the most appropriate way to assess pain in AD.
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Experimental gerontology · Mar 2014
Review Meta AnalysisGender and telomere length: systematic review and meta-analysis.
It is widely believed that females have longer telomeres than males, although results from studies have been contradictory. ⋯ Telomere length is longer in females than males, although this difference was not universally found in studies that did not use Southern blot methods. Further research on explanations for the methodological differences is required.