Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
-
Randomized Controlled Trial
Cigarettes with different nicotine levels affect sensory perception and levels of biomarkers of exposure in adult smokers.
Few clinical studies involving cigarettes have provided a comprehensive picture of smoke exposure, test article characterization, and insights into sensory properties combined. The purpose of these pilot studies was to determine whether cigarettes with different levels of nicotine but similar tar levels would affect sensory experience or smoking behavior so as to significantly alter levels of selected biomarkers of exposure (BOE). ⋯ These studies demonstrate that abrupt increases or decreases in nicotine and the resulting sensory changes impact BOE through changes in intensity or frequency of smoking.