Prostate cancer and prostatic diseases
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Prostate Cancer Prostatic Dis. · Nov 2018
Meta AnalysisIncidence and risk factors of suicide after a prostate cancer diagnosis: a meta-analysis of observational studies.
Whether the diagnosis of prostate cancer is a contributory psychological stress that causes excess risk of suicide among affected men remains controversial. We performed a meta-analysis of previous studies to investigate suicide incidence and associated risk factors among men diagnosed with prostate cancer. ⋯ Current evidence indicates that the risk of suicide is increased among men diagnosed with prostate cancer, particularly those aged 75 years or older, <12 months after diagnosis, and treated with hormonal therapy. Healthcare providers should be aware of these special populations considered at high risk of suicide. Hence, further research should be conducted to refine suicide risk assessment with detection tools and to develop the best practices for prevention.
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Prostate Cancer Prostatic Dis. · Jun 2016
Review Meta AnalysisPatient experience in the treatment of metastatic castration-resistant prostate cancer: state of the science.
Contemporary therapies for metastatic castration-resistant prostate cancer (mCRPC) have shown survival improvements, which do not account for patient experience and health-related quality of life (HRQoL). ⋯ Recently published randomized clinical trials of new agents for mCRPC have captured elements of the patient experience while on treatment. Further research is required to standardize methods for measuring, quantifying and reporting on HRQoL and pain in patients with mCRPC in the clinical practice setting.