Diseases of the colon and rectum
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Multicenter Study Comparative Study
Perioperative statin therapy is not associated with reduced risk of anastomotic leakage after colorectal resection.
Anastomotic leakage is a serious complication of colorectal surgery. Several studies have demonstrated the beneficial pleiotropic effects of statins, and preliminary studies have suggested that perioperative statin treatment may be associated with reduced risk of anastomotic leakage. ⋯ Perioperative statin therapy was not significantly associated with reduced anastomotic leakage rate after colorectal resection with primary anastomosis.