Fertility and sterility
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Fertility and sterility · Jul 2008
Randomized Controlled TrialTibolone reverses the cognitive effects caused by leuprolide acetate administration, improving mood and quality of life in patients with symptomatic uterine leiomyomas.
To investigate the effects of tibolone co-administration with GnRH agonist treatment in terms of cognition, mood, and quality of life. ⋯ Tibolone administration reverses the deleterious effect on cognition that is caused by leuprolide acetate depot and improves mood and quality of life in patients who receive GnRH agonist for symptomatic uterine leiomyomas.