Fertility and sterility
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Fertility and sterility · May 2009
Randomized Controlled Trial Comparative StudyIbuprofen and paracetamol for pain relief during medical abortion: a double-blind randomized controlled study.
To determine the efficacy of a nonsteroidal anti-inflammatory drug vs. paracetamol in pain relief during medical abortion and to evaluate whether nonsteroidal anti-inflammatory drugs interfere with the action of misoprostol. ⋯ Ibuprofen was found to be more effective than paracetamol for pain reduction during medical abortion. A history of surgical or medical abortion was predictive for high pain scores. Despite its anti-prostaglandin effects, ibuprofen use did not interfere with the action of misoprostol.