Undersea Hyperbar M
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Undersea Hyperbar M · Jul 2012
Randomized Controlled TrialHyperbaric oxygen for post-concussion syndrome: design of Department of Defense clinical trials.
The current wars in the Middle East have resulted in between 10-20% of U. S. service members with mild traumatic brain injury (mTBI). While anecdotal reports have associated hyperbaric oxygen (HBO2) with improved outcomes after mTBI, controlled research is lacking. ⋯ Compression pressures will range from 1.2 atm abs (sham) to 2.4 atm abs, and oxygen concentration will range from room air (sham and control) to 100%. Outcomes measures include both subjective and objective measures performed at baseline, at exposure completion, and at three to 12 months' follow-up. This integrated program of clinical trials investigating the efficacy of HBO2 in service members with persistent symptoms following mTBI exposure will be important to define practice guidelines and, if needed, for the development of definitive clinical trials in this population.