Can J Emerg Med
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Review Meta Analysis Comparative Study
Early goal-directed therapy versus usual care in the management of septic shock.
Clinical question Does early goal-directed therapy decrease mortality when compared with usual care? Article chosen Angus DC, Barnato AE, Bell D, et al. A systematic review and meta-analysis of early goal-directed therapy for septic shock: the ARISE, ProCESS and ProMISe Investigators. Intensive Care Med 2015;41(9):1549-60. doi:10.1007/s00134-015-3822-1.