J Emerg Med
-
Randomized Controlled Trial
Phenobarbital for acute alcohol withdrawal: a prospective randomized double-blind placebo-controlled study.
Acute alcohol withdrawal syndrome (AAWS) is encountered in patients presenting acutely to the Emergency Department (ED) and often requires pharmacologic management. ⋯ A single dose of i.v. phenobarbital combined with a symptom-guided lorazepam-based alcohol withdrawal protocol resulted in decreased ICU admission and did not cause increased adverse outcomes.