J Trauma
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Clinical Trial Controlled Clinical Trial
The impact of hypoxia and hyperventilation on outcome after paramedic rapid sequence intubation of severely head-injured patients.
An increase in mortality has been documented in association with paramedic rapid sequence intubation (RSI) of severely head-injured patients. This analysis explores the impact of hypoxia and hyperventilation on outcome. ⋯ Hyperventilation and severe hypoxia during paramedic RSI are associated with an increase in mortality.
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Little is known about the influence of regionalization of trauma care on pediatric trauma care delivery. The purpose of this study was to estimate whether formal adoption of a statewide trauma system was associated with hospital admission patterns of injured children. ⋯ Trauma designation in Washington was associated with a shift in admissions from nondesignated hospitals to pediatric trauma hospitals.
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The safety and efficacy of poly-N-acetyl glucosamine (p-GlcNAc) gels were compared with standard agents in three different dog studies to assess abdominal venous collaterals, bleeding esophageal varices, and bleeding gastric varices. ⋯ F2 and F4 poly-N-acetyl glucosamine gels are promising therapeutic agents for venous and variceal hemostasis.
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Investigations were performed to determine whether poly-N-acetyl glucosamine (p-GlcNAc) induces hemostasis by the activation of platelets. ⋯ Poly-N-acetyl glucosamine fiber material promotes hemostasis by the activation of platelets.