Journal of cellular physiology
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Bile acids are steroid acids found in the bile of mammals. The bile acid conjugate tauroursodeoxycholic acid (TUDCA) is neuroprotective in different animal models of stroke and neurological diseases. We have previously shown that TUDCA has anti-inflammatory effects on glial cell cultures and in a mouse model of acute neuroinflammation. ⋯ J. Cell. Physiol. 232: 2231-2245, 2017. © 2016 Wiley Periodicals, Inc.